Endothelial cells by inactivation of VHL gene direct angiogenesis, not vasculogenesis via Twist1 accumulation associated with hemangioblastoma neovascularization. [electronic resource]
- Scientific reports 07 2017
- 5463 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-017-05833-9 doi
Adolescent Adult Aged Apoptosis Cell Cycle--genetics Cell Line, Tumor Cell Proliferation Cerebellar Neoplasms--blood supply Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Ontology HEK293 Cells Hemangioblastoma--blood supply Human Umbilical Vein Endothelial Cells--cytology Humans Male Middle Aged Molecular Sequence Annotation Neovascularization, Pathologic--genetics Nuclear Proteins--genetics Protein Isoforms--antagonists & inhibitors RNA, Small Interfering--genetics Signal Transduction Twist-Related Protein 1--genetics Von Hippel-Lindau Tumor Suppressor Protein--antagonists & inhibitors