Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival. [electronic resource]
- Gynecologic oncology 09 2017
- 588-595 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
1095-6859
10.1016/j.ygyno.2017.07.003 doi
Age Factors Aged DNA Methylation DNA Mismatch Repair--genetics Disease-Free Survival Endometrial Neoplasms--chemistry Epigenesis, Genetic Female Gene Silencing Humans Lymphatic Metastasis Microsatellite Instability Middle Aged MutL Protein Homolog 1--analysis Mutation Neoplasm Grading Neoplasm Invasiveness--genetics Neoplasm Recurrence, Local--genetics Neoplasm Staging Tumor Burden--genetics