Orillion, Ashley

Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 09 2017 - 5187-5201 p. digital

Publication Type: Journal Article

1557-3265

10.1158/1078-0432.CCR-17-0741 doi


Animals
Benzamides--administration & dosage
Carcinoma, Non-Small-Cell Lung--drug therapy
Carcinoma, Renal Cell--drug therapy
Disease Models, Animal
Histone Deacetylase Inhibitors--administration & dosage
Humans
Immune Tolerance--immunology
Immunotherapy--methods
Mice
Myeloid-Derived Suppressor Cells--immunology
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Pyridines--administration & dosage
Tumor Microenvironment--drug effects