Trinidad, A G

Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells. [electronic resource] - Oncogene 11 2017 - 6164-6176 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2017.224 doi


Cell Cycle--genetics
Cell Line, Tumor
Cell Proliferation--genetics
Colorectal Neoplasms--genetics
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
Humans
Lung Neoplasms--genetics
Mutation
Protein Kinases--genetics
Proto-Oncogene Proteins p21(ras)--genetics
Signal Transduction--genetics