Corte, James R <br/><br/>
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  08 2017 
 - 3833-3839 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2017.06.058  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amides--chemical synthesis<br/>Crystallography, X-Ray<br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Factor XIa--antagonists & inhibitors<br/>Humans<br/>Macrocyclic Compounds--chemical synthesis<br/>Models, Molecular<br/>Molecular Structure<br/>Serine Proteinase Inhibitors--chemical synthesis<br/>Structure-Activity Relationship