TY - GEN AU - Quintana,Anita M AU - Hernandez,Jose A AU - Gonzalez,Cesar G TI - Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development SN - 1932-6203 PY - 2017///0922 KW - Animals KW - Anticholesteremic Agents KW - pharmacology KW - Atorvastatin KW - Benzophenones KW - Body Patterning KW - drug effects KW - Cell Differentiation KW - Cholesterol KW - biosynthesis KW - Chondrocytes KW - Craniofacial Abnormalities KW - genetics KW - Embryo, Nonmammalian KW - Enzyme Inhibitors KW - Gene Expression Regulation, Developmental KW - Hedgehog Proteins KW - Humans KW - Hydroxymethylglutaryl CoA Reductases KW - Hydroxymethylglutaryl-CoA Synthase KW - Neural Crest KW - Piperidines KW - Pyridines KW - Signal Transduction KW - Terpenes KW - antagonists & inhibitors KW - Zebrafish KW - Zebrafish Proteins KW - Zinc Finger Protein GLI1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0180856 ER -