TY  - GEN
AU  - Zhang,Chi
AU  - Lai,Maria B
AU  - Khandan,Lavan
AU  - Lee,Lindsey A
AU  - Chen,Zhe
AU  - Junge,Harald J
TI  - Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function
SN  - 2041-1723
PY  - 2018///1219
KW  - ATPases Associated with Diverse Cellular Activities
KW  - metabolism
KW  - Animals
KW  - Blood-Brain Barrier
KW  - Endocytosis
KW  - Endosomal Sorting Complexes Required for Transport
KW  - Endosomes
KW  - Endothelial Cells
KW  - Eye Diseases, Hereditary
KW  - genetics
KW  - Eye Proteins
KW  - Familial Exudative Vitreoretinopathies
KW  - Frizzled Receptors
KW  - HEK293 Cells
KW  - HeLa Cells
KW  - Humans
KW  - In Vitro Techniques
KW  - Lysosomes
KW  - Mice
KW  - Multivesicular Bodies
KW  - Mutation
KW  - Neovascularization, Physiologic
KW  - Nerve Tissue Proteins
KW  - Protein Transport
KW  - Retina
KW  - Retinal Diseases
KW  - Retinal Vessels
KW  - growth & development
KW  - Ubiquitination
KW  - Vacuolar Proton-Translocating ATPases
KW  - Wnt Signaling Pathway
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/ncomms16050
ER  -