Ghorab, Mostafa M <br/><br/>
VEGFR-2 inhibitors and apoptosis inducers: synthesis and molecular design of new benzo[g]quinazolin bearing benzenesulfonamide moiety.  [electronic resource] 

 -  Journal of enzyme inhibition and medicinal chemistry  Dec 2017 
 - 893-907 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1475-6374 
<br/><br/><label>Standard No.: </label>10.1080/14756366.2017.1334650  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Apoptosis--drug effects<br/>Breast--cytology<br/>Caspase 3--metabolism<br/>Catalytic Domain<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Line<br/>Drug Screening Assays, Antitumor<br/>Enzyme Activation<br/>Humans<br/>Inhibitory Concentration 50<br/>MCF-7 Cells<br/>Molecular Docking Simulation<br/>Piperidines--pharmacology<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Quinazolines--chemical synthesis<br/>Spectrum Analysis--methods<br/>Sulfonamides--chemistry<br/>Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors<br/>bcl-2-Associated X Protein--metabolism<br/>Benzenesulfonamides