Emery, Caroline M <br/><br/>
BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity.  [electronic resource] 

 -  Molecular cancer research : MCR  10 2017 
 - 1431-1444 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1557-3125 
<br/><br/><label>Standard No.: </label>10.1158/1541-7786.MCR-17-0211  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Site<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Colorectal Neoplasms--drug therapy<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>MAP Kinase Kinase 1--chemistry<br/>MAP Kinase Kinase 2--chemistry<br/>MAP Kinase Signaling System--drug effects<br/>Models, Molecular<br/>Mutation<br/>Phosphorylation<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Structure, Secondary<br/>Proto-Oncogene Proteins B-raf--chemistry<br/>raf Kinases--metabolism