TY - GEN AU - Richer,Amanda L AU - Cala,Jacqueline M AU - O'Brien,Kelley AU - Carson,Vashti M AU - Inge,Landon J AU - Whitsett,Timothy G TI - WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer SN - 1538-7445 PY - 2017///1031 KW - AMP-Activated Protein Kinases KW - Animals KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Cycle Checkpoints KW - drug effects KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Cell Survival KW - Drug Evaluation, Preclinical KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Mice KW - Mice, Transgenic KW - Mutation KW - genetics KW - Nuclear Proteins KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - deficiency KW - Protein-Tyrosine Kinases KW - Proto-Oncogene Proteins p21(ras) KW - Pyrazoles KW - pharmacology KW - Pyrimidines KW - Pyrimidinones KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/0008-5472.CAN-16-3565 ER -