TY  - GEN
AU  - Machlus,Kellie R
AU  - Wu,Stephen K
AU  - Vijey,Prakrith
AU  - Soussou,Thomas S
AU  - Liu,Zhi-Jian
AU  - Shacham,Eran
AU  - Unger,T J
AU  - Kashyap,Trinayan
AU  - Klebanov,Boris
AU  - Sola-Visner,Martha
AU  - Crochiere,Marsha
AU  - Italiano,Joseph E
AU  - Landesman,Yosef
TI  - Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis
SN  - 1528-0020
PY  - 2017///0925
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Blood Platelets
KW  - Bone Marrow
KW  - Cell Count
KW  - Cell Differentiation
KW  - Dose-Response Relationship, Drug
KW  - Fetus
KW  - pathology
KW  - Hydrazines
KW  - adverse effects
KW  - Liver
KW  - embryology
KW  - Megakaryocytes
KW  - Mice, Knockout
KW  - Platelet Activation
KW  - Signal Transduction
KW  - Stem Cells
KW  - cytology
KW  - Thrombocytopenia
KW  - blood
KW  - Thrombopoiesis
KW  - Thrombopoietin
KW  - metabolism
KW  - Triazoles
N1  - Publication Type: Clinical Trial, Phase I; Journal Article
UR  - https://doi.org/10.1182/blood-2016-11-752840
ER  -