Machlus, Kellie R <br/><br/>
Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis.  [electronic resource] 

 -  Blood  08 2017 
 - 1132-1143 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase I; Journal Article 
<br/><br/><label>ISSN: </label>1528-0020 
<br/><br/><label>Standard No.: </label>10.1182/blood-2016-11-752840  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Blood Platelets--drug effects<br/>Bone Marrow--drug effects<br/>Cell Count<br/>Cell Differentiation--drug effects<br/>Dose-Response Relationship, Drug<br/>Fetus--pathology<br/>Hydrazines--adverse effects<br/>Liver--embryology<br/>Megakaryocytes--drug effects<br/>Mice, Knockout<br/>Platelet Activation--drug effects<br/>Signal Transduction--drug effects<br/>Stem Cells--cytology<br/>Thrombocytopenia--blood<br/>Thrombopoiesis--drug effects<br/>Thrombopoietin--metabolism<br/>Triazoles--adverse effects