TY - GEN AU - Ross,Fiona A AU - Hawley,Simon A AU - Auciello,F Romana AU - Gowans,Graeme J AU - Atrih,Abdelmadjid AU - Lamont,Douglas J AU - Hardie,D Grahame TI - Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib SN - 2451-9448 PY - 2017///0926 KW - AMP-Activated Protein Kinase Kinases KW - AMP-Activated Protein Kinases KW - antagonists & inhibitors KW - Allosteric Regulation KW - Binding Sites KW - Catalytic Domain KW - Cell-Free System KW - Enzyme Activation KW - drug effects KW - HEK293 Cells KW - HeLa Cells KW - Humans KW - Indans KW - pharmacology KW - Indoles KW - chemistry KW - Mutagenesis, Site-Directed KW - Niacinamide KW - analogs & derivatives KW - Phenylurea Compounds KW - Phosphorylation KW - Protein Isoforms KW - genetics KW - Protein Serine-Threonine Kinases KW - metabolism KW - Pyrimidines KW - Sorafenib KW - Sulfonamides KW - src-Family Kinases N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.chembiol.2017.05.021 ER -