TY - GEN AU - Yoon,Suyoung AU - Kim,Jong Hyun AU - Koh,Yura AU - Tran,Phuong-Thao AU - Ann,Jihyae AU - Yoon,Ina AU - Jang,Jayun AU - Kim,Won Kyung AU - Lee,Sangkook AU - Lee,Jiyoun AU - Kim,Sunghoon AU - Lee,Jeewoo TI - Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors SN - 1464-3391 PY - 2017///1121 KW - Cell Line, Tumor KW - Drug Discovery KW - Drug Screening Assays, Antitumor KW - HEK293 Cells KW - Humans KW - Leucine-tRNA Ligase KW - metabolism KW - Mass Spectrometry KW - methods KW - Mechanistic Target of Rapamycin Complex 1 KW - antagonists & inhibitors KW - Phosphorylation KW - Proton Magnetic Resonance Spectroscopy KW - Ribosomal Protein S6 Kinases KW - Sulfonic Acids KW - chemistry N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmc.2017.06.002 ER -