Yoon, Suyoung <br/><br/>
Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  08 2017 
 - 4145-4152 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2017.06.002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Line, Tumor<br/>Drug Discovery<br/>Drug Screening Assays, Antitumor<br/>HEK293 Cells<br/>Humans<br/>Leucine-tRNA Ligase--metabolism<br/>Mass Spectrometry--methods<br/>Mechanistic Target of Rapamycin Complex 1--antagonists & inhibitors<br/>Phosphorylation<br/>Proton Magnetic Resonance Spectroscopy<br/>Ribosomal Protein S6 Kinases--metabolism<br/>Sulfonic Acids--chemistry