TY - GEN AU - Fowler,Andy AU - Koenen,RĂ¼diger AU - Hilbert,James AU - Blatchford,Jon AU - Kappeler,Dominik AU - Benediktus,Ewald AU - Wood,Chester AU - Gupta,Abhya TI - Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel CRTH2 Antagonist BI 1021958 at Single Oral Doses in Healthy Men and Multiple Oral Doses in Men and Women With Well-Controlled Asthma SN - 1552-4604 PY - 2018///0530 KW - Administration, Oral KW - Adult KW - Anti-Asthmatic Agents KW - adverse effects KW - Area Under Curve KW - Asthma KW - drug therapy KW - Cross-Over Studies KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Eosinophils KW - drug effects KW - Female KW - Food-Drug Interactions KW - physiology KW - Half-Life KW - Humans KW - Male KW - Receptors, Immunologic KW - antagonists & inhibitors KW - Receptors, Prostaglandin KW - Single-Blind Method N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial UR - https://doi.org/10.1002/jcph.947 ER -