Ortega, Jose Antonio

Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells. [electronic resource] - Journal of medicinal chemistry 07 2017 - 5800-5815 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/acs.jmedchem.7b00472 doi


Acid Ceramidase--antagonists & inhibitors
Animals
Antineoplastic Agents--blood
Benzimidazoles--blood
Cell Line, Tumor
Cell Survival--drug effects
Drug Stability
Enzyme Inhibitors--blood
HEK293 Cells
Humans
Melanoma--drug therapy
Mice