TY - GEN AU - van der Heijden,Thomas AU - Kritikou,Eva AU - Venema,Wouter AU - van Duijn,Janine AU - van Santbrink,Peter J AU - Slütter,Bram AU - Foks,Amanda C AU - Bot,Ilze AU - Kuiper,Johan TI - NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report SN - 1524-4636 PY - 2017///0808 KW - Animals KW - Anti-Inflammatory Agents KW - pharmacology KW - Apolipoproteins E KW - deficiency KW - Atherosclerosis KW - genetics KW - Carotid Arteries KW - drug effects KW - Carotid Artery Diseases KW - Cells, Cultured KW - Cholesterol KW - Crystallization KW - Dendritic Cells KW - Diet, Western KW - Disease Models, Animal KW - Female KW - Furans KW - Genetic Predisposition to Disease KW - Heterocyclic Compounds, 4 or More Rings KW - Indenes KW - Inflammasomes KW - antagonists & inhibitors KW - Intercellular Adhesion Molecule-1 KW - Interleukin-1beta KW - metabolism KW - Lipopolysaccharides KW - Macrophages KW - Mice, Inbred C57BL KW - Mice, Knockout KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Necrosis KW - Phenotype KW - Plaque, Atherosclerotic KW - RNA, Messenger KW - Signal Transduction KW - Sulfonamides KW - Sulfones KW - Time Factors KW - Vascular Cell Adhesion Molecule-1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1161/ATVBAHA.117.309575 ER -