Liu, Sai-Lan
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition. [electronic resource]
- Cancer letters 08 2017
- 117-130 p. digital
Publication Type: Journal Article
ISSN: 1872-7980
Standard No.: 10.1016/j.canlet.2017.05.022 doi
Subjects--Topical Terms: Adult Animals Antineoplastic Agents--pharmacology Apoptosis--drug effects Biomarkers, Tumor--genetics Carcinoma--drug therapy Cell Cycle Proteins--genetics Cell Line, Tumor Cisplatin--pharmacology Disease-Free Survival Dose-Response Relationship, Drug Drug Resistance, Neoplasm Epithelial-Mesenchymal Transition--drug effects Female Gene Expression Regulation, Neoplastic Humans Intracellular Signaling Peptides and Proteins--genetics Kaplan-Meier Estimate Male Mice, Inbred BALB C Mice, Nude Middle Aged Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms--drug therapy Neoplasm Grading Neoplasm Staging Phenotype Proportional Hazards Models RNA Interference Time Factors Transcription, Genetic Transfection Wnt Signaling Pathway--drug effects Xenograft Model Antitumor Assays