Liu, Sai-Lan

TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition. [electronic resource] - Cancer letters 08 2017 - 117-130 p. digital

Publication Type: Journal Article

1872-7980

10.1016/j.canlet.2017.05.022 doi


Adult
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Biomarkers, Tumor--genetics
Carcinoma--drug therapy
Cell Cycle Proteins--genetics
Cell Line, Tumor
Cisplatin--pharmacology
Disease-Free Survival
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Epithelial-Mesenchymal Transition--drug effects
Female
Gene Expression Regulation, Neoplastic
Humans
Intracellular Signaling Peptides and Proteins--genetics
Kaplan-Meier Estimate
Male
Mice, Inbred BALB C
Mice, Nude
Middle Aged
Nasopharyngeal Carcinoma
Nasopharyngeal Neoplasms--drug therapy
Neoplasm Grading
Neoplasm Staging
Phenotype
Proportional Hazards Models
RNA Interference
Time Factors
Transcription, Genetic
Transfection
Wnt Signaling Pathway--drug effects
Xenograft Model Antitumor Assays