TY  - GEN
AU  - Tchasovnikarova,Iva A
AU  - Timms,Richard T
AU  - Douse,Christopher H
AU  - Roberts,Rhys C
AU  - Dougan,Gordon
AU  - Kingston,Robert E
AU  - Modis,Yorgo
AU  - Lehner,Paul J
TI  - Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2
SN  - 1546-1718
PY  - 2017///1004
KW  - Adenosine Triphosphatases
KW  - metabolism
KW  - CRISPR-Cas Systems
KW  - Charcot-Marie-Tooth Disease
KW  - genetics
KW  - Chromatin Assembly and Disassembly
KW  - Epigenetic Repression
KW  - Gene Silencing
KW  - HeLa Cells
KW  - Heterochromatin
KW  - Histone Code
KW  - Histone-Lysine N-Methyltransferase
KW  - Histones
KW  - Humans
KW  - Lysine
KW  - chemistry
KW  - Methylation
KW  - Multiprotein Complexes
KW  - Mutation, Missense
KW  - Neurons
KW  - Protein Domains
KW  - Protein Interaction Mapping
KW  - Protein Methyltransferases
KW  - Protein Processing, Post-Translational
KW  - Transcription Factors
KW  - Transgenes
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/ng.3878
ER  -