TY - GEN AU - Lacher,Sonja M AU - Bruttger,Julia AU - Kalt,Bettina AU - Berthelet,Jean AU - Rajalingam,Krishnaraj AU - Wörtge,Simone AU - Waisman,Ari TI - HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival SN - 2041-4889 PY - 2018///0223 KW - Animals KW - Cell Count KW - Cell Death KW - drug effects KW - Cell Survival KW - Gene Deletion KW - Hydroxymethylglutaryl CoA Reductases KW - deficiency KW - Integrases KW - metabolism KW - Lymphocyte Activation KW - Mevalonic Acid KW - analogs & derivatives KW - Mice, Inbred C57BL KW - Phenotype KW - Polyisoprenyl Phosphates KW - pharmacology KW - Protein Prenylation KW - T-Lymphocytes KW - cytology KW - T-Lymphocytes, Regulatory N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/cddis.2017.221 ER -