Lacher, Sonja M HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival. [electronic resource] - Cell death & disease 05 2017 - e2824 p. digital Publication Type: Journal Article; Research Support, Non-U.S. Gov't ISSN: 2041-4889 Standard No.: 10.1038/cddis.2017.221 doi Subjects--Topical Terms: AnimalsCell CountCell Death--drug effectsCell Survival--drug effectsGene DeletionHydroxymethylglutaryl CoA Reductases--deficiencyIntegrases--metabolismLymphocyte Activation--drug effectsMevalonic Acid--analogs & derivativesMice, Inbred C57BLPhenotypePolyisoprenyl Phosphates--pharmacologyProtein Prenylation--drug effectsT-Lymphocytes--cytologyT-Lymphocytes, Regulatory--cytology