Lacher, Sonja M

HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival. [electronic resource] - Cell death & disease 05 2017 - e2824 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-4889

10.1038/cddis.2017.221 doi


Animals
Cell Count
Cell Death--drug effects
Cell Survival--drug effects
Gene Deletion
Hydroxymethylglutaryl CoA Reductases--deficiency
Integrases--metabolism
Lymphocyte Activation--drug effects
Mevalonic Acid--analogs & derivatives
Mice, Inbred C57BL
Phenotype
Polyisoprenyl Phosphates--pharmacology
Protein Prenylation--drug effects
T-Lymphocytes--cytology
T-Lymphocytes, Regulatory--cytology