TY  - GEN
AU  - Teng,Teng
AU  - Tsai,Jennifer Hc
AU  - Puyang,Xiaoling
AU  - Seiler,Michael
AU  - Peng,Shouyong
AU  - Prajapati,Sudeep
AU  - Aird,Daniel
AU  - Buonamici,Silvia
AU  - Caleb,Benjamin
AU  - Chan,Betty
AU  - Corson,Laura
AU  - Feala,Jacob
AU  - Fekkes,Peter
AU  - Gerard,Baudouin
AU  - Karr,Craig
AU  - Korpal,Manav
AU  - Liu,Xiang
AU  - T Lowe,Jason
AU  - Mizui,Yoshiharu
AU  - Palacino,James
AU  - Park,Eunice
AU  - Smith,Peter G
AU  - Subramanian,Vanitha
AU  - Wu,Zhenhua Jeremy
AU  - Zou,Jian
AU  - Yu,Lihua
AU  - Chicas,Agustin
AU  - Warmuth,Markus
AU  - Larsen,Nicholas
AU  - Zhu,Ping
TI  - Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex
SN  - 2041-1723
PY  - 2018///1211
KW  - Adenosine
KW  - chemistry
KW  - Alternative Splicing
KW  - Carrier Proteins
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Cryoelectron Microscopy
KW  - Crystallography, X-Ray
KW  - Epoxy Compounds
KW  - Exons
KW  - Fatty Alcohols
KW  - HCT116 Cells
KW  - Humans
KW  - Introns
KW  - Macrolides
KW  - Mass Spectrometry
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - Phosphoproteins
KW  - Protein Binding
KW  - Protein Conformation
KW  - Pyrans
KW  - RNA Interference
KW  - RNA Splicing Factors
KW  - RNA-Binding Proteins
KW  - Recombinant Proteins
KW  - Sequence Analysis, RNA
KW  - Spiro Compounds
KW  - Spliceosomes
KW  - metabolism
KW  - Trans-Activators
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/ncomms15522
ER  -