McNally, Jonathan P <br/><br/>
Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  06 2017 
 - E4782-E4791 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1703683114  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cell Cycle Checkpoints--drug effects<br/>DNA Damage--immunology<br/>Disease Models, Animal<br/>Drug Evaluation, Preclinical<br/>Encephalomyelitis, Autoimmune, Experimental--immunology<br/>Etoposide--administration & dosage<br/>Humans<br/>Immune System Diseases--immunology<br/>Lymphocyte Activation<br/>Lymphohistiocytosis, Hemophagocytic--immunology<br/>Mice<br/>Mice, 129 Strain<br/>Mice, Inbred BALB C<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>Mice, Transgenic<br/>Multiple Sclerosis--immunology<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Signal Transduction--immunology<br/>T-Lymphocytes--drug effects<br/>Tumor Suppressor Protein p53--immunology