TY  - GEN
AU  - Quinti,Luisa
AU  - Dayalan Naidu,Sharadha
AU  - Träger,Ulrike
AU  - Chen,Xiqun
AU  - Kegel-Gleason,Kimberly
AU  - Llères,David
AU  - Connolly,Colúm
AU  - Chopra,Vanita
AU  - Low,Cho
AU  - Moniot,Sébastien
AU  - Sapp,Ellen
AU  - Tousley,Adelaide R
AU  - Vodicka,Petr
AU  - Van Kanegan,Michael J
AU  - Kaltenbach,Linda S
AU  - Crawford,Lisa A
AU  - Fuszard,Matthew
AU  - Higgins,Maureen
AU  - Miller,James R C
AU  - Farmer,Ruth E
AU  - Potluri,Vijay
AU  - Samajdar,Susanta
AU  - Meisel,Lisa
AU  - Zhang,Ningzhe
AU  - Snyder,Andrew
AU  - Stein,Ross
AU  - Hersch,Steven M
AU  - Ellerby,Lisa M
AU  - Weerapana,Eranthie
AU  - Schwarzschild,Michael A
AU  - Steegborn,Clemens
AU  - Leavitt,Blair R
AU  - Degterev,Alexei
AU  - Tabrizi,Sarah J
AU  - Lo,Donald C
AU  - DiFiglia,Marian
AU  - Thompson,Leslie M
AU  - Dinkova-Kostova,Albena T
AU  - Kazantsev,Aleksey G
TI  - KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
SN  - 1091-6490
PY  - 2018///0514
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Brain
KW  - drug effects
KW  - Cells, Cultured
KW  - Cytokines
KW  - metabolism
KW  - Disease Models, Animal
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - Huntington Disease
KW  - genetics
KW  - Kelch-Like ECH-Associated Protein 1
KW  - chemistry
KW  - MPTP Poisoning
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Microglia
KW  - Middle Aged
KW  - NF-E2-Related Factor 2
KW  - Neural Stem Cells
KW  - Neuroprotective Agents
KW  - pharmacology
KW  - Protein Conformation
KW  - Rats
KW  - Signal Transduction
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1614943114
ER  -