Quinti, Luisa <br/><br/>
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  06 2017 
 - E4676-E4685 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1614943114  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Animals<br/>Brain--drug effects<br/>Cells, Cultured<br/>Cytokines--metabolism<br/>Disease Models, Animal<br/>Female<br/>HEK293 Cells<br/>Humans<br/>Huntington Disease--genetics<br/>Kelch-Like ECH-Associated Protein 1--chemistry<br/>MPTP Poisoning--metabolism<br/>Macrophages--drug effects<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Microglia--drug effects<br/>Middle Aged<br/>NF-E2-Related Factor 2--chemistry<br/>Neural Stem Cells--metabolism<br/>Neuroprotective Agents--pharmacology<br/>Protein Conformation--drug effects<br/>Rats<br/>Signal Transduction