TY - GEN AU - Bustos,Victor AU - Pulina,Maria V AU - Bispo,Ashley AU - Lam,Alison AU - Flajolet,Marc AU - Gorelick,Fred S AU - Greengard,Paul TI - Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion SN - 1091-6490 PY - 2018///0612 KW - Amyloid beta-Peptides KW - genetics KW - Animals KW - Annexin A2 KW - metabolism KW - Autophagosomes KW - Autophagy KW - physiology KW - Brain KW - Cell Line, Tumor KW - Lysosomes KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Microscopy, Confocal KW - Neuroblastoma KW - Neurons KW - Phagosomes KW - Phosphorylation KW - Presenilin-1 KW - Qa-SNARE Proteins KW - R-SNARE Proteins KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1073/pnas.1705240114 ER -