TY  - GEN
AU  - Wu,Hao
AU  - Esteve,Eduardo
AU  - Tremaroli,Valentina
AU  - Khan,Muhammad Tanweer
AU  - Caesar,Robert
AU  - Mannerås-Holm,Louise
AU  - Ståhlman,Marcus
AU  - Olsson,Lisa M
AU  - Serino,Matteo
AU  - Planas-Fèlix,Mercè
AU  - Xifra,Gemma
AU  - Mercader,Josep M
AU  - Torrents,David
AU  - Burcelin,Rémy
AU  - Ricart,Wifredo
AU  - Perkins,Rosie
AU  - Fernàndez-Real,José Manuel
AU  - Bäckhed,Fredrik
TI  - Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
SN  - 1546-170X
PY  - 2017///0911
KW  - Animals
KW  - Bile Acids and Salts
KW  - metabolism
KW  - DNA, Bacterial
KW  - analysis
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Double-Blind Method
KW  - Fatty Acids, Volatile
KW  - Fecal Microbiota Transplantation
KW  - Feces
KW  - chemistry
KW  - Female
KW  - Gastrointestinal Microbiome
KW  - genetics
KW  - Germ-Free Life
KW  - Glucose Tolerance Test
KW  - Humans
KW  - Hypoglycemic Agents
KW  - therapeutic use
KW  - In Vitro Techniques
KW  - Male
KW  - Metagenomics
KW  - Metformin
KW  - Mice
KW  - Middle Aged
N1  - Publication Type: Journal Article; Randomized Controlled Trial
UR  - https://doi.org/10.1038/nm.4345
ER  -