Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. [electronic resource]
- Nature medicine Jul 2017
- 850-858 p. digital
Animals Bile Acids and Salts--metabolism DNA, Bacterial--analysis Diabetes Mellitus, Type 2--drug therapy Double-Blind Method Fatty Acids, Volatile--metabolism Fecal Microbiota Transplantation Feces--chemistry Female Gastrointestinal Microbiome--genetics Germ-Free Life Glucose Tolerance Test Humans Hypoglycemic Agents--therapeutic use In Vitro Techniques Male Metagenomics Metformin--therapeutic use Mice Middle Aged