TY  - GEN
AU  - Perry,Matthew W D
AU  - Björhall,Karin
AU  - Bonn,Britta
AU  - Carlsson,Johan
AU  - Chen,Yunhua
AU  - Eriksson,Anders
AU  - Fredlund,Linda
AU  - Hao,Hai'e
AU  - Holden,Neil S
AU  - Karabelas,Kostas
AU  - Lindmark,Helena
AU  - Liu,Feifei
AU  - Pemberton,Nils
AU  - Petersen,Jens
AU  - Rodrigo Blomqvist,Sandra
AU  - Smith,Reed W
AU  - Svensson,Tor
AU  - Terstiege,Ina
AU  - Tyrchan,Christian
AU  - Yang,Wenzhen
AU  - Zhao,Shuchun
AU  - Öster,Linda
TI  - Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration
SN  - 1520-4804
PY  - 2017///0811
KW  - Administration, Inhalation
KW  - Animals
KW  - Biological Availability
KW  - Chemistry Techniques, Synthetic
KW  - Drug Design
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Enzyme Inhibitors
KW  - administration & dosage
KW  - Half-Life
KW  - Isoenzymes
KW  - antagonists & inhibitors
KW  - Mice, Transgenic
KW  - Permeability
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Rats
KW  - Solubility
KW  - Structure-Activity Relationship
KW  - Thiazoles
KW  - chemistry
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/acs.jmedchem.7b00401
ER  -