Perry, Matthew W D <br/><br/>
Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration.  [electronic resource] 

 -  Journal of medicinal chemistry  06 2017 
 - 5057-5071 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.7b00401  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Inhalation<br/>Animals<br/>Biological Availability<br/>Chemistry Techniques, Synthetic<br/>Drug Design<br/>Drug Evaluation, Preclinical--methods<br/>Enzyme Inhibitors--administration & dosage<br/>Half-Life<br/>Isoenzymes--antagonists & inhibitors<br/>Mice, Transgenic<br/>Permeability<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Rats<br/>Solubility<br/>Structure-Activity Relationship<br/>Thiazoles--chemistry