TY - GEN AU - Nezu,Masahiro AU - Suzuki,Norio AU - Yamamoto,Masayuki TI - Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression SN - 1421-9670 PY - 2018///0402 KW - Acute Kidney Injury KW - drug therapy KW - Animals KW - Clinical Trials as Topic KW - Diabetes Mellitus, Type 2 KW - Disease Models, Animal KW - Disease Progression KW - Gene Expression Regulation KW - drug effects KW - Glomerular Filtration Rate KW - Humans KW - Kelch-Like ECH-Associated Protein 1 KW - antagonists & inhibitors KW - Kidney Tubules KW - Mice KW - Molecular Targeted Therapy KW - methods KW - NF-E2-Related Factor 2 KW - genetics KW - Oleanolic Acid KW - analogs & derivatives KW - Oxidative Stress KW - Proteasome Endopeptidase Complex KW - metabolism KW - Proteolysis KW - Reactive Oxygen Species KW - Renal Insufficiency, Chronic KW - etiology KW - Signal Transduction KW - Ubiquitination N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1159/000475890 ER -