TY  - GEN
AU  - Aarts,Suzanne A B M
AU  - Seijkens,Tom T P
AU  - Kusters,Pascal J H
AU  - van der Pol,Susanne M A
AU  - Zarzycka,Barbara
AU  - Heijnen,Priscilla D A M
AU  - Beckers,Linda
AU  - den Toom,Myrthe
AU  - Gijbels,Marion J J
AU  - Boon,Louis
AU  - Weber,Christian
AU  - de Vries,Helga E
AU  - Nicolaes,Gerry A F
AU  - Dijkstra,Christine D
AU  - Kooij,Gijs
AU  - Lutgens,Esther
TI  - Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation
SN  - 1742-2094
PY  - 2018///0326
KW  - Animals
KW  - Anti-Inflammatory Agents
KW  - pharmacology
KW  - CD40 Antigens
KW  - metabolism
KW  - Cell Movement
KW  - drug effects
KW  - Cells, Cultured
KW  - Cerebellum
KW  - Disease Models, Animal
KW  - Encephalomyelitis, Autoimmune, Experimental
KW  - chemically induced
KW  - Gene Expression Regulation
KW  - Humans
KW  - Matrix Metalloproteinase 9
KW  - genetics
KW  - Mice
KW  - Monocytes
KW  - Myelin-Oligodendrocyte Glycoprotein
KW  - toxicity
KW  - Nitric Oxide Synthase Type I
KW  - Peptide Fragments
KW  - Rats
KW  - Rats, Inbred Lew
KW  - Reactive Oxygen Species
KW  - Spinal Cord
KW  - TNF Receptor-Associated Factor 6
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s12974-017-0875-9
ER  -