Sanders, Matthew A <br/><br/>
Pharmacological targeting of RAD6 enzyme-mediated translesion synthesis overcomes resistance to platinum-based drugs.  [electronic resource] 

 -  The Journal of biological chemistry  06 2017 
 - 10347-10363 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1083-351X 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M117.792192  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Breast Neoplasms--drug therapy<br/>Cell Line, Tumor<br/>Colonic Neoplasms--drug therapy<br/>DNA Repair--drug effects<br/>DNA Replication--drug effects<br/>DNA, Neoplasm--biosynthesis<br/>Drug Resistance, Neoplasm--drug effects<br/>Enzyme Inhibitors--pharmacology<br/>Female<br/>Humans<br/>Mice<br/>Mice, Nude<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Organoplatinum Compounds--pharmacology<br/>Oxaliplatin<br/>Ubiquitin-Conjugating Enzymes--antagonists & inhibitors<br/>Xenograft Model Antitumor Assays