Satoh, Ryosuke

Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells. [electronic resource] - Genes to cells : devoted to molecular & cellular mechanisms Jul 2017 - 608-618 p. digital

Publication Type: Journal Article

1365-2443

10.1111/gtc.12499 doi


3T3 Cells
Animals
Antineoplastic Agents--chemistry
Apoptosis--drug effects
Benzyl Alcohols--chemistry
Butadienes--pharmacology
Cell Line, Tumor
Cell Transformation, Neoplastic--drug effects
Enzyme Inhibitors--pharmacology
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Expression Regulation, Enzymologic--drug effects
Humans
MAP Kinase Kinase 1--antagonists & inhibitors
Melanocytes--cytology
Melanoma--drug therapy
Mice
Nitriles--pharmacology
Phosphorylation--drug effects
Signal Transduction--drug effects