TY - GEN AU - Kang,Sookjin AU - Kim,Wooseong AU - Jeong,Seongkeun AU - Lee,Yonghyun AU - Nam,Joon AU - Lee,Sunyoung AU - Jung,Yunjin TI - Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid SN - 1873-4596 PY - 2018///0426 KW - Animals KW - Anti-Inflammatory Agents KW - therapeutic use KW - Colonic Neoplasms KW - drug therapy KW - HCT116 Cells KW - Heme Oxygenase-1 KW - metabolism KW - Humans KW - Hypochlorous Acid KW - Inflammation KW - Inflammatory Bowel Diseases KW - Kelch-Like ECH-Associated Protein 1 KW - Male KW - Mesalamine KW - NF-E2-Related Factor 2 KW - Oxidation-Reduction KW - Protein Binding KW - Rats KW - Rats, Sprague-Dawley N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.freeradbiomed.2017.04.366 ER -