TY  - GEN
AU  - Wilkinson,David J
AU  - Wang,Hui
AU  - Habgood,Angela
AU  - Lamb,Heather K
AU  - Thompson,Paul
AU  - Hawkins,Alastair R
AU  - Désilets,Antoine
AU  - Leduc,Richard
AU  - Steinmetzer,Torsten
AU  - Hammami,Maya
AU  - Lee,Melody S
AU  - Craik,Charles S
AU  - Watson,Sharon
AU  - Lin,Hua
AU  - Milner,Jennifer M
AU  - Rowan,Andrew D
TI  - Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms
SN  - 2326-5205
PY  - 2017///0821
KW  - ADAMTS4 Protein
KW  - drug effects
KW  - ADAMTS5 Protein
KW  - Aged
KW  - Aged, 80 and over
KW  - Aggrecans
KW  - Animals
KW  - Antibodies, Neutralizing
KW  - pharmacology
KW  - Blotting, Western
KW  - Cartilage, Articular
KW  - Endopeptidases
KW  - Female
KW  - Gene Expression Profiling
KW  - Humans
KW  - Immunohistochemistry
KW  - In Vitro Techniques
KW  - Low Density Lipoprotein Receptor-Related Protein-1
KW  - Male
KW  - Matrix Metalloproteinases
KW  - Membrane Proteins
KW  - antagonists & inhibitors
KW  - Menisci, Tibial
KW  - surgery
KW  - Mice
KW  - Middle Aged
KW  - Osteoarthritis, Knee
KW  - metabolism
KW  - Real-Time Polymerase Chain Reaction
KW  - Recombinant Proteins
KW  - Serine Endopeptidases
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/art.40133
ER  -