TY - GEN AU - Moore,Kathleen N AU - Borghaei,Hossein AU - O'Malley,David M AU - Jeong,Woondong AU - Seward,Shelly M AU - Bauer,Todd M AU - Perez,Raymond P AU - Matulonis,Ursula A AU - Running,Kelli L AU - Zhang,Xiaoyan AU - Ponte,Jose F AU - Ruiz-Soto,Rodrigo AU - Birrer,Michael J TI - Phase 1 dose-escalation study of mirvetuximab soravtansine (IMGN853), a folate receptor α-targeting antibody-drug conjugate, in patients with solid tumors SN - 1097-0142 PY - 2017///0911 KW - Adult KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal, Humanized KW - therapeutic use KW - Antineoplastic Agents KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Carcinoma, Ovarian Epithelial KW - Carcinoma, Renal Cell KW - Diarrhea KW - chemically induced KW - Disease Progression KW - Dose-Response Relationship, Drug KW - Endometrial Neoplasms KW - Fatigue KW - Female KW - Humans KW - Hypophosphatemia KW - Immunoconjugates KW - Keratitis KW - Kidney Neoplasms KW - Lung Neoplasms KW - Male KW - Maximum Tolerated Dose KW - Maytansine KW - analogs & derivatives KW - Middle Aged KW - Neoplasms KW - Neoplasms, Glandular and Epithelial KW - Ovarian Neoplasms KW - Vision Disorders N1 - Publication Type: Clinical Trial, Phase I; Journal Article UR - https://doi.org/10.1002/cncr.30736 ER -