TY - GEN AU - Yuan,Xuejun AU - Qi,Hui AU - Li,Xiang AU - Wu,Fan AU - Fang,Jian AU - Bober,Eva AU - Dobreva,Gergana AU - Zhou,Yonggang AU - Braun,Thomas TI - Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice SN - 1558-8238 PY - 2017///0926 KW - Animals KW - Cell Hypoxia KW - Cell Proliferation KW - Embryo, Mammalian KW - pathology KW - Female KW - Gene Expression KW - Gene Expression Regulation, Developmental KW - Gene Silencing KW - HEK293 Cells KW - Heart Defects, Congenital KW - etiology KW - Histone Deacetylases KW - metabolism KW - Homeobox Protein Nkx-2.5 KW - genetics KW - Humans KW - LIM-Homeodomain Proteins KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Myocardium KW - Pregnancy KW - Signal Transduction KW - Sirtuin 1 KW - Spatio-Temporal Analysis KW - Transcription Factors N1 - Publication Type: Journal Article UR - https://doi.org/10.1172/JCI88725 ER -