TY - GEN AU - Martinelli,Leonardo K B AU - Rotta,Mariane AU - Villela,Anne D AU - Rodrigues-Junior,Valnês S AU - Abbadi,Bruno L AU - Trindade,Rogério V AU - Petersen,Guilherme O AU - Danesi,Giuliano M AU - Nery,Laura R AU - Pauli,Ivani AU - Campos,Maria M AU - Bonan,Carla D AU - de Souza,Osmar Norberto AU - Basso,Luiz A AU - Santos,Diogenes S TI - Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme SN - 2045-2322 PY - 2019///0802 KW - Animals KW - Antitubercular Agents KW - pharmacology KW - Bacterial Proteins KW - antagonists & inhibitors KW - Cell Line KW - Chlorocebus aethiops KW - Computer Simulation KW - Enzyme Inhibitors KW - Humans KW - Kinetics KW - Mice KW - Microbial Sensitivity Tests KW - Mycobacterium tuberculosis KW - drug effects KW - Oxidoreductases KW - RAW 264.7 Cells KW - Thermodynamics KW - Tuberculosis KW - microbiology KW - Vero Cells N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep46696 ER -