TY - GEN AU - da Silva-Coelho,Pedro AU - Kroeze,Leonie I AU - Yoshida,Kenichi AU - Koorenhof-Scheele,Theresia N AU - Knops,Ruth AU - van de Locht,Louis T AU - de Graaf,Aniek O AU - Massop,Marion AU - Sandmann,Sarah AU - Dugas,Martin AU - Stevens-Kroef,Marian J AU - Cermak,Jaroslav AU - Shiraishi,Yuichi AU - Chiba,Kenichi AU - Tanaka,Hiroko AU - Miyano,Satoru AU - de Witte,Theo AU - Blijlevens,Nicole M A AU - Muus,Petra AU - Huls,Gerwin AU - van der Reijden,Bert A AU - Ogawa,Seishi AU - Jansen,Joop H TI - Clonal evolution in myelodysplastic syndromes SN - 2041-1723 PY - 2018///1115 KW - Aged KW - Angiogenesis Inhibitors KW - therapeutic use KW - Biomarkers, Tumor KW - genetics KW - Bone Marrow Cells KW - drug effects KW - Clonal Evolution KW - Disease Management KW - Disease Progression KW - Drug Resistance, Neoplasm KW - Female KW - Follow-Up Studies KW - GTP Phosphohydrolases KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Lenalidomide KW - Male KW - Membrane Proteins KW - Middle Aged KW - Monitoring, Physiologic KW - Mutation KW - Myelodysplastic Syndromes KW - drug therapy KW - Proto-Oncogene Proteins p21(ras) KW - Thalidomide KW - analogs & derivatives KW - Tumor Suppressor Protein p53 KW - Exome Sequencing N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncomms15099 ER -