TY  - GEN
AU  - Ghareb,Nagat
AU  - Elshihawy,Hosam A
AU  - Abdel-Daim,Mohamed M
AU  - Helal,Mohamed A
TI  - Novel pyrazoles and pyrazolo[1,2-a]pyridazines as selective COX-2 inhibitors; Ultrasound-assisted synthesis, biological evaluation, and DFT calculations
SN  - 1464-3405
PY  - 2017///1219
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - chemical synthesis
KW  - Binding Sites
KW  - drug effects
KW  - Celecoxib
KW  - chemistry
KW  - Cyclization
KW  - Cyclooxygenase 2 Inhibitors
KW  - Enzyme Assays
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Molecular Docking Simulation
KW  - Pyrazoles
KW  - Pyridazines
KW  - Quantum Theory
KW  - Quinones
KW  - Spodoptera
KW  - Ultrasonic Waves
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2017.04.020
ER  -