Petrilli, Alejandra M

Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. [electronic resource] - Oncotarget May 2017 - 31666-31681 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.15912 doi


Antineoplastic Agents--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Cyclin D1--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Focal Adhesion Protein-Tyrosine Kinases--metabolism
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Imidazoles--pharmacology
MAP Kinase Signaling System--drug effects
Neurilemmoma--genetics
Neurofibromin 2--deficiency
Paxillin--metabolism
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Pyridazines--pharmacology
Receptors, Platelet-Derived Growth Factor--metabolism
STAT3 Transcription Factor--metabolism
Schwann Cells--drug effects
Signal Transduction--drug effects
src-Family Kinases--metabolism