Petrilli, Alejandra M
Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. [electronic resource]
- Oncotarget May 2017
- 31666-31681 p. digital
Publication Type: Journal Article
ISSN: 1949-2553
Standard No.: 10.18632/oncotarget.15912 doi
Subjects--Topical Terms: Antineoplastic Agents--pharmacology Cell Line, Tumor Cell Survival--drug effects Cyclin D1--metabolism Cyclin-Dependent Kinase Inhibitor p27--metabolism Focal Adhesion Protein-Tyrosine Kinases--metabolism G1 Phase Cell Cycle Checkpoints--drug effects Humans Imidazoles--pharmacology MAP Kinase Signaling System--drug effects Neurilemmoma--genetics Neurofibromin 2--deficiency Paxillin--metabolism Protein Kinase Inhibitors--pharmacology Proto-Oncogene Proteins c-akt--metabolism Pyridazines--pharmacology Receptors, Platelet-Derived Growth Factor--metabolism STAT3 Transcription Factor--metabolism Schwann Cells--drug effects Signal Transduction--drug effects src-Family Kinases--metabolism