TY - GEN AU - Wang,Hui Qin AU - Halilovic,Ensar AU - Li,Xiaoyan AU - Liang,Jinsheng AU - Cao,Yichen AU - Rakiec,Daniel P AU - Ruddy,David A AU - Jeay,Sebastien AU - Wuerthner,Jens U AU - Timple,Noelito AU - Kasibhatla,Shailaja AU - Li,Nanxin AU - Williams,Juliet A AU - Sellers,William R AU - Huang,Alan AU - Li,Fang TI - Combined ALK and MDM2 inhibition increases antitumor activity and overcomes resistance in human SN - 2050-084X PY - 2018///0212 KW - Anaplastic Lymphoma Kinase KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Disease Models, Animal KW - Drug Resistance, Neoplasm KW - Heterografts KW - Humans KW - Mice, Nude KW - Neoplasm Transplantation KW - Neuroblastoma KW - drug therapy KW - Proto-Oncogene Proteins c-mdm2 KW - antagonists & inhibitors KW - Pyrimidines KW - Receptor Protein-Tyrosine Kinases KW - Sulfones N1 - Publication Type: Journal Article UR - https://doi.org/10.7554/eLife.17137 ER -