TY  - GEN
AU  - Hoyt,Scott B
AU  - Taylor,Jerry
AU  - London,Clare
AU  - Ali,Amjad
AU  - Ujjainwalla,Feroze
AU  - Tata,Jim
AU  - Struthers,Mary
AU  - Cully,Doris
AU  - Wisniewski,Tom
AU  - Ren,Ning
AU  - Bopp,Charlene
AU  - Sok,Andrea
AU  - Verras,Andreas
AU  - McMasters,Daniel
AU  - Chen,Qing
AU  - Tung,Elaine
AU  - Tang,Wei
AU  - Salituro,Gino
AU  - Clemas,Joe
AU  - Zhou,Gaochao
AU  - MacNeil,Douglas
AU  - Duffy,Ruth
AU  - Xiong,Yusheng
TI  - Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension
SN  - 1464-3405
PY  - 2017///1219
KW  - Animals
KW  - Antihypertensive Agents
KW  - chemical synthesis
KW  - Aromatase Inhibitors
KW  - Cell Line
KW  - Cricetulus
KW  - Cytochrome P-450 CYP11B2
KW  - antagonists & inhibitors
KW  - Cytochrome P-450 CYP2D6 Inhibitors
KW  - Humans
KW  - Hypertension
KW  - drug therapy
KW  - Indazoles
KW  - Macaca mulatta
KW  - Male
KW  - Rats, Sprague-Dawley
KW  - Stereoisomerism
KW  - Steroid 11-beta-Hydroxylase
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2017.04.021
ER  -