Hoyt, Scott B <br/><br/>
Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  06 2017 
 - 2384-2388 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2017.04.021  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antihypertensive Agents--chemical synthesis<br/>Aromatase Inhibitors--chemical synthesis<br/>Cell Line<br/>Cricetulus<br/>Cytochrome P-450 CYP11B2--antagonists & inhibitors<br/>Cytochrome P-450 CYP2D6 Inhibitors--chemical synthesis<br/>Humans<br/>Hypertension--drug therapy<br/>Indazoles--chemical synthesis<br/>Macaca mulatta<br/>Male<br/>Rats, Sprague-Dawley<br/>Stereoisomerism<br/>Steroid 11-beta-Hydroxylase--antagonists & inhibitors