Desroy, Nicolas <br/><br/>
Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis.  [electronic resource] 

 -  Journal of medicinal chemistry  05 2017 
 - 3580-3590 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.7b00032  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Humans<br/>Idiopathic Pulmonary Fibrosis--drug therapy<br/>Imidazoles--pharmacology<br/>Mice<br/>Mice, Knockout<br/>Phosphoric Diester Hydrolases--drug effects<br/>Pyrimidines--pharmacology<br/>Rats