TY  - GEN
AU  - Saleheen,Danish
AU  - Natarajan,Pradeep
AU  - Armean,Irina M
AU  - Zhao,Wei
AU  - Rasheed,Asif
AU  - Khetarpal,Sumeet A
AU  - Won,Hong-Hee
AU  - Karczewski,Konrad J
AU  - O'Donnell-Luria,Anne H
AU  - Samocha,Kaitlin E
AU  - Weisburd,Benjamin
AU  - Gupta,Namrata
AU  - Zaidi,Mozzam
AU  - Samuel,Maria
AU  - Imran,Atif
AU  - Abbas,Shahid
AU  - Majeed,Faisal
AU  - Ishaq,Madiha
AU  - Akhtar,Saba
AU  - Trindade,Kevin
AU  - Mucksavage,Megan
AU  - Qamar,Nadeem
AU  - Zaman,Khan Shah
AU  - Yaqoob,Zia
AU  - Saghir,Tahir
AU  - Rizvi,Syed Nadeem Hasan
AU  - Memon,Anis
AU  - Hayyat Mallick,Nadeem
AU  - Ishaq,Mohammad
AU  - Rasheed,Syed Zahed
AU  - Memon,Fazal-Ur-Rehman
AU  - Mahmood,Khalid
AU  - Ahmed,Naveeduddin
AU  - Do,Ron
AU  - Krauss,Ronald M
AU  - MacArthur,Daniel G
AU  - Gabriel,Stacey
AU  - Lander,Eric S
AU  - Daly,Mark J
AU  - Frossard,Philippe
AU  - Danesh,John
AU  - Rader,Daniel J
AU  - Kathiresan,Sekar
TI  - Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity
SN  - 1476-4687
PY  - 2017///0822
KW  - 1-Alkyl-2-acetylglycerophosphocholine Esterase
KW  - deficiency
KW  - Apolipoprotein C-III
KW  - Cohort Studies
KW  - Consanguinity
KW  - Coronary Disease
KW  - blood
KW  - Cytochrome P450 Family 2
KW  - genetics
KW  - DNA Mutational Analysis
KW  - Dietary Fats
KW  - pharmacology
KW  - Exome
KW  - Fasting
KW  - Female
KW  - Gene Deletion
KW  - Gene Frequency
KW  - Genes
KW  - Genetic Association Studies
KW  - methods
KW  - Homozygote
KW  - Humans
KW  - Interleukin-8
KW  - Male
KW  - Middle Aged
KW  - Myocardial Infarction
KW  - Neuregulins
KW  - Pakistan
KW  - Pedigree
KW  - Phenotype
KW  - Phosphoproteins
KW  - Postprandial Period
KW  - RNA Splice Sites
KW  - Reverse Genetics
KW  - Sodium-Hydrogen Exchangers
KW  - Triglycerides
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/nature22034
ER  -