Becker, Lindsay A <br/><br/>
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.  [electronic resource] 

 -  Nature  04 2017 
 - 367-371 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1476-4687 
<br/><br/><label>Standard No.: </label>10.1038/nature22038  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyotrophic Lateral Sclerosis--genetics<br/>Animals<br/>Ataxin-2--deficiency<br/>Central Nervous System--metabolism<br/>Cytoplasmic Granules--metabolism<br/>DNA-Binding Proteins--chemistry<br/>Disease Progression<br/>Female<br/>Gene Knockdown Techniques<br/>Humans<br/>Longevity<br/>Male<br/>Mice<br/>Mice, Knockout<br/>Mice, Transgenic<br/>Motor Skills--physiology<br/>Oligonucleotides, Antisense--administration & dosage<br/>Protein Aggregation, Pathological--genetics<br/>Stress, Physiological<br/>Survival Analysis