TY - GEN AU - Leksa,N C AU - Chiu,P-L AU - Bou-Assaf,G M AU - Quan,C AU - Liu,Z AU - Goodman,A B AU - Chambers,M G AU - Tsutakawa,S E AU - Hammel,M AU - Peters,R T AU - Walz,T AU - Kulman,J D TI - The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein SN - 1538-7836 PY - 2018///0423 KW - Crystallography, X-Ray KW - Factor VIII KW - administration & dosage KW - HEK293 Cells KW - Half-Life KW - Hemophilia A KW - drug therapy KW - Hemorrhage KW - Humans KW - Immunoglobulin Fc Fragments KW - Kinetics KW - Mass Spectrometry KW - Microscopy, Electron KW - Peptide Fragments KW - chemistry KW - Protein Domains KW - Recombinant Fusion Proteins KW - Scattering, Small Angle KW - Surface Plasmon Resonance KW - X-Ray Diffraction N1 - Publication Type: Journal Article UR - https://doi.org/10.1111/jth.13700 ER -